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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
10.91
Human Site:
Y581
Identified Species:
20
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
Y581
R
L
P
F
P
T
G
Y
K
R
Q
R
E
Y
E
Chimpanzee
Pan troglodytes
XP_508321
684
75407
Y581
R
L
P
F
P
S
G
Y
K
R
Q
R
E
Y
E
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
Y581
R
L
P
F
P
T
G
Y
K
R
Q
R
E
Y
E
Dog
Lupus familis
XP_534086
793
86791
R692
P
F
P
S
S
Y
K
R
Q
R
E
Y
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
K581
L
P
F
P
T
G
Y
K
R
P
R
E
Y
E
E
Rat
Rattus norvegicus
XP_002725626
681
74519
K581
L
P
F
P
T
G
Y
K
R
P
R
E
Y
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
P539
G
P
P
G
H
P
L
P
H
I
G
Y
K
R
H
Chicken
Gallus gallus
XP_421015
633
66869
T536
G
P
G
R
P
G
L
T
A
V
K
P
R
C
T
Frog
Xenopus laevis
Q6NU13
800
83727
P690
N
M
Q
P
P
G
R
P
L
P
P
I
T
S
S
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
Y543
K
F
E
D
E
E
E
Y
D
S
E
M
D
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
D502
S
E
L
D
D
F
I
D
D
G
D
C
E
E
D
Honey Bee
Apis mellifera
XP_395689
579
67372
E500
L
E
D
F
I
D
D
E
V
E
E
G
N
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
K534
K
P
P
I
M
H
V
K
R
G
R
I
M
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
93.3
100
26.6
N.A.
6.6
0
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
40
N.A.
20
20
N.A.
13.3
13.3
13.3
26.6
N.A.
13.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
0
8
16
8
8
8
8
16
0
8
0
8
24
24
% D
% Glu:
0
16
8
0
8
8
8
8
0
8
24
16
39
24
39
% E
% Phe:
0
16
16
31
0
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
16
0
8
8
0
31
24
0
0
16
8
8
0
0
0
% G
% His:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
8
0
8
0
0
8
0
16
0
0
0
% I
% Lys:
16
0
0
0
0
0
8
24
24
0
8
0
8
0
0
% K
% Leu:
24
24
8
0
0
0
16
0
8
0
0
0
0
0
0
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
39
47
24
39
8
0
16
0
24
8
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
24
0
0
0
0
% Q
% Arg:
24
0
0
8
0
0
8
8
24
31
24
24
8
8
0
% R
% Ser:
8
0
0
8
8
8
0
0
0
8
0
0
0
8
16
% S
% Thr:
0
0
0
0
16
16
0
8
0
0
0
0
8
0
8
% T
% Val:
0
0
0
0
0
0
8
0
8
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
16
31
0
0
0
16
16
24
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _